Biomedical Informatics Research Group

A stylised image of a brain in blue and turquoise

The Biomedical Informatics Group, part of ARU's Medical Technology Research Centre (MTRC), has research interests in utilising computational and machine learning techniques to leverage the potential of healthcare, medical and genomic data and produce optimised solutions for healthcare processes, independent living, medical diagnostic techniques and prognosis of disease.

Key publications

A stylised image of a brain in green, yellow and blue

Todd, J., Cardellicchio, P., Swami, V., Cardini, F., Aspell, J. E., 2021. Weaker implicit interoception is associated with more negative body image: Evidence from gastric-alpha phase amplitude coupling and the heartbeat evoked potential. Cortex, 143, pp. 254-266.

Sze, S., Pellicori, P., Zhang, J., Weston, J., Squire, I. B., Clark, A. L., 2021 Effect of frailty on treatment, hospitalisation and death in patients with chronic heart failure. Clinical Research in Cardiology. doi: 10.1007/s00392-020-01792-w

Hanning, I., Pellicori, P., Zhang, J., Bhandari, S., Clark, A., Shah, P., 2021. The Effect of Digoxin on Renal Function in Patients with Heart Failure. BMC Nephrology. Availabl on Research Square ahead of publication. doi: 10.21203/

Machado, B. H. B., Frame, J., Zhang, J., Najlah, M., 2021. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial. Aesthetic Plast. Surg. doi: 10.1007/s00266-020-02035-z

Stather, P., Petty, C., Langthorne, H., Rayner, E., Zhang, J., Hayden, K., Howard, A., 2021. A randomised controlled clinical trial comparing the effectiveness of bandaging compared to the JuxtaCuresTM device in the management of people with venous ulceration: Feasibility Study. Phlebology. doi: 10.1177/0268355520988226

Hameed, N., Shabut, A., Hameed, F., Cirstea, S., Hossain, A., 2021. Achievements of neural network in skin lesions classification. In: El-Baz, A. S., Suri, J., 2021. State of the Art in Neural Networks and Their Applications (London: Elsevier). ISBN: 978-0-12-819740-0

Zhang, J., Hayden, K., Jackson, R., Schutte, R., 2020. Association of red and processed meat consumption with cardiovascular morbidity and mortality in participants with and without obesity: A prospective cohort study. Clinical Nutrition, S0261-5614(20)30705-6. doi: 10.1016/j.clnu.2020.12.030

Zhang, J., Hayden, K., Jackson, R., Schutte, R., 2020. Associations of weight changes with all-cause, cancer and cardiovascular mortality: A prospective cohort study. Public Health in Practice, 2:100065. doi: 10.1016/j.puhip.2020.100065

Aggius-Vella, E., Kolarik, A. J., Gori, M., Cirstea, S., Campus, C., Moore, B. C. J., Pardhan, S., 2020. Comparison of auditory spatial bisection and minimum audible angle in front, lateral, and back space. Scientific Reports, 10:6279. doi: 10.1038/s41598-020-62983-z

Kolarik, A. J., Raman, R., Moore, B. C. J., Cirstea, S., Gopalakrishnan, S., Pardhan, S., 2020. The accuracy of auditory spatial judgments in the visually impaired is dependent on sound source distance. Scientific Reports, 10:7169. doi: 10.1038/s41598-020-64306-8

Ricci, C., Leitzmann, M. F., Freisling, H., Schutte, A. E., Schutte, R., Kruger, S. H., Smuts, C. M., Pieters, M., 2020. Diet and sedentary behaviour in relation to mortality in US adults with a cardiovascular condition. Results from the National Health and Nutrition Examination Survey linked to the US mortality registry. British Journal of Nutrition, 124, pp. 1329-1337.

Mul, C., Cardini, F., Stagg, S. D., Sadeghi-Esfahlani, S., Kiourtsoglou, D., Cardellicchio, P., Aspell, J. E, 2019. Altered bodily self-consciousness and peripersonal space in autism. Autism, 23(8).

Hameed N., Hameed F., Shabut A., Khan S., Cirstea S., Hossain A., 2019. An Intelligent Computer-Aided Scheme for Classifying Multiple Skin Lesions. Computers, 8(3), pp. 62. doi: 10.3390/computers8030062

Mul, C., Stagg, S. D., Herbelin, B., Aspell, J. E., 2018. The feeling of me feeling for you: Interoception, alexithymia and empathy in autism. Journal of Autism and Developmental Disorders, 48, pp. 2953-2967.

Maktabdar Oghaz, M., Maarof, M. A., Rohani, M. F., Zainal, A., Shaid, S. Z. M., 2017. An optimized skin texture model using gray-level co-occurrence matrix. Neural Computing and Applications, 31(6), pp. 1835–1853.

Pamment, J., Aspell, J. E., 2016. Putting pain out of mind with an ‘out of body’ illusion. European Journal of Pain, 21(2), pp. 334-342.

Kolarik, A. J., Moore, B. C. J., Zahorik, P., Cirstea, S., Pardhan, S., 2016. Auditory distance perception in humans: a review of cues, development, neuronal bases, and effects of sensory loss. Attention, Perception, and Psychophysics, 78(2), pp. 373-395. doi: 10.3758/s13414-015-1015-1

Yaghoubyan, S. H., Maarof, M. A., Zainal, A., Kiani, M. J., Rad, F., Maktabdar Oghaz, M., 2016. A Robust Keypoint Descriptor Based on Tomographic Image Reconstruction Using Heuristic Genetic Algorithm and Principal Component Analysis Techniques. Journal of Computational and Theoretical Nanoscience, 13(8), pp. 5554–5568.

Maktabdar Oghaz, M., Maarof, M. A., Zainal, A., Rohani, M. F., Yaghoubyan, S. H., 2015. A Hybrid Color Space for Skin Detection Using Genetic Algorithm Heuristic Search and Principal Component Analysis Technique. PLOS ONE, 10(8), p.e0134828.

Aspell, J. E., Heydrich, L., Marillier, G., Lavanchy, T., Herbelin, B., Blanke, O., 2013. Turning body and self inside out: visualized heartbeats alter bodily self-consciousness and tactile perception. Psychological Science, 24(12), pp. 2445-2453.

Read more about key publications.

ARU offers the following courses in this area:

Contact us

For more information, contact Dr Silvia Cirstea at or the MTRC at