Dr Jufen Zhang

Medical Statistician

Faculty:Faculty of Health, Education, Medicine and Social Care


Location: Chelmsford

Dr Zhang is a medical statistician. She is interested in clinical trials research and application of statistical methods to analyse clinical data.



Dr Jufen Zhang received her PhD from the University of Exeter. Before joining Anglia Ruskin University she worked as a Statistical Analyst at Hull York Medical School, University of Hull.


  • PhD in Statistical Computing
  • MSc in Applied Statistics
  • BSc in Mathematics
  • Chartered Statistician, Royal Statistical Society

Selected recent publications

Shah R. Mohdnazri, Grigoris V. Karamasis, Firas Al-Janabi, Christopher M. Cook, James Hampton-Till, Jufen Zhang, Rasha Al-Lamee, Jason N. Dungu, Swamy Gedela , Kare H. Tang, Paul A. Kelly, Justin E. Davies, John R. Davies, Thomas R. Keeble. The Impact of Coronary Chronic Total Occlusion (CTO) Percutaneous Coronary Intervention (PCI) Upon Donor Vessel Fractional Flow Reserve (FFR) and Instantaneous Wave-Free Ratio (iFR): Implications for Physiology-Guided PCI in Patients With CTO study. Catheterization and Cardiovascular Interventions. 2018 in press.

Pellicori, P., Urbinati, A., Zhang, J., Joseph,A.C., Costanzo, P., Lukaschuk, E., Capucci, A. and Cleland, J.G.F. Clinical and prognostic relationships of pulmonary artery to aorta diameter ratio in patients with heart failure. A cardiac magnetic resonance imaging study. Clin Cardiol. 2018 Jan;41(1):20-27. doi: 10.1002/clc.22840

Theodora Nikolaidou, Pierpaolo Pellicori, Jufen Zhang, Syed Kazmi, Kevin M Goode, John G Cleland, Andrew L Clark. Prevalence, predictors and prognostic implications of PR interval prolongation in patients with heart failure. Clin Res Cardiol. 2017 Sep 15. doi: 10.1007/s00392-017-1162-6.

Sze S, Zhang J, Pellicori P, Morgan D, Hoye A, Clark AL. Prognostic value of simple frailty and malnutrition screening tools in patients with acute heart failure due to left ventricular systolic dysfunction. Clin Res Cardiol. 2017 Jul;106(7):533-541.

Pierpaolo Pellicori, Andrew L. Clark, Anna Kallvikbacka-Bennett, Jufen Zhang, Alessia Urbinati, Luca Monzo, Riet Dierckx, Stefan D Anker, John GF Cleland. Non-Invasive measurement of Right Atrial Pressure by Near-Infrared Spectroscopy: Preliminary Experience. A Report from the SICA-HF Study. European Journal of Heart Failure.2017, 19(7), pp. 883-892.

Jufen Zhang, Kenneth Y-K. Wong, Andrew L. Clark, John G.F. Cleland. Exploring the relation between changes in NT-proBNP and renal function in patients with suspected heart failure using structural equation modelling. International Journal of Cardiology. 233 (2017) 67–72.

Jufen Zhang, Riet Dierckx, Kevin Mohee, Andrew L. Clark, John G. Cleland. Xanthine Oxidase Inhibition for the Treatment of Cardiovascular Disease: An Updated Systematic Review and Meta-Analysis. ESC Heart Failure 2017 Feb; 4(1): 40–45.

Pellicori P, Urbinati A, Shah P, MacNamara A, Kazmi S, Dierckx R, Zhang J, Cleland JG, Clark AL. What proportion of patients with chronic heart failure are eligible for sacubitril–valsartan? Eur J Heart Fail. 2016 Jun;19(6):768-778.

Pellicori P, Cleland JG, Zhang J, Bennett A, Urbinati A, Shah P, Kazmi S, Clark AL. Cardiac Dysfunction, Congestion and Loop Diuretics: Their Relationship to Prognosis in Heart Failure. Cardiovascular Drugs and Therapy, 2016 Dec;30(6):599-609.

Cleland JG, Zhang J, Pellicori P, Dicken B, Dierckx R, Shoaib A, Wong K, Rigby A, Goode K, Clark AL. Prevalence and Outcomes of Anemia and Hematinic Deficiencies in Patients with Chronic Heart Failure. JAMA Cardiol. 2016 Aug 1;1(5):539-47

Jufen Zhang, James Hobkirk, Sean Carroll, Pierpaolo Pellicori, Andrew L. Clark, John G.F. Cleland. Exploring quality of life in patients with and without heart failure. International Journal of Cardiology 202 (2016) 676–684

Pierpaolo Pellicori, Anil C. Joseph, Jufen Zhang, Elena Lukaschuk, Nasser Sherwi, Christos V. Bourantas, Huan Loh, Andrew L. Clark, John GF Cleland. The Relationship of QRS Morphology with Cardiac Structure and Function in Patients with Heart Failure. Clin Res Cardiol. 2015 Nov;104(11):935-45

Pierpaolo Pellicori, Jufen Zhang, Elena Lukaschuk, Anil C Joseph, Christos V Bourantas, Huan Loh, Thanjavur Bragadeesh, Andrew L Clark, John GF Cleland. Left Atrial Function Measured by Cardiac Magnetic Resonance Imaging in Patients with Heart Failure: Clinical Associations and Prognostic Value. European Heart Journal (2015) 36, 733–743

Farag Mohamed, Mabote Thato, Shoaib Ahmad, Zhang Jufen, Nabhan Ashraf F, Clark Andrew L, Cleland John G. Hydralazine and Nitrates Alone or Combined for the Management of Chronic Heart Failure: A Systematic Review. International Journal of Cardiology (2015), pp. 61-69

Dierckx R, Cleland JGF, Pellicori P, Zhang J, Clark AL. "If home telemonitoring reduces mortality in heart failure, is this just due to better guideline-based treatment?" Journal of Telemedicine and Telecare, 2015, 0(0) 10-9

Pierluigi Costanzo, MD, MSc; John G.F. Cleland, MD; Pierpaolo Pellicori, MD; Andrew L. Clark, MD; David Hepburn, MD; Eric S. Kilpatrick, MD; Pasquale Perrone-Filardi, MD, PhD; Jufen Zhang, MSc, PhD; and Stephen L. Atkin, MD, PhD. The Obesity Paradox in Type 2 Diabetes Mellitus: Relationship of Body Mass Index to Prognosis: A Cohort Study. Ann Intern Med. 2015;162(9):610-618

Pierpaolo Pellicori, Anna Kallvikbacka-Bennett, Riet Dierckx, Jufen Zhang, Paola Putzu, Joe Cuthbert, Vennela Boyalla, Ahmed Shoaib, Andrew L Clark, John GF Cleland. Prognostic Significance of Ultrasound-Assessed Jugular Vein Distensibility in Heart Failure, Heart 2015 Jul;101(14):1149-58

Nasser Sherwi, Kenneth Wong, Jufen Zhang, Pierpaolo Pellicori, Olga Khaleva, Christos Bourantas, Azam Torabi, Andrew Clark and John G Cleland. The Prevalence of Extra-cranial Carotid Artery Disease in Chronic Heart Failure. Cardiology and Angiology: An International Journal. 3(1): 17-26, 2015

Damien Cullington, Kevin M. Goode, Jufen Zhang, John G.F. Cleland, Andrew L. Clark. Is Heart Rate Important for Patients With Heart Failure in Atrial Fibrillation? JACC Heart Failure. 2014; 2(3):213-220

J Zhang, R Dierckx, JG Cleland. “Xanthine Oxidase Inhibition for the Treatment of Cardiovascular Disease: A Systematic Review and Meta-Analysis”. Cardiovascular Therapeutics. April 2014, volume 32, issue 2, pages 57–58

Book chapters

John G.F. Cleland, Azam Torabi, Jufen Zhang, and Raj K. Chelliah, Chapter: Medical therapy for chronic heart failure, 43: Antithrombotic agents, Oxford Textbook of Heart Failure. 978-0-19-957772-9 | Hardback | July 2011

Recent presentations and conferences

The factors associated with heart failure hospitalization rates in heart failure patients with normal and reduced left ventricular ejection fraction. ESC Heart Failure congress 2016

Predicting Survival in Patients with Heart Failure Based on Variables Used in the MAGGIC model. The European Society of Cardiology (ESC) Heart Failure 2015

Dynamic prediction using joint models in patients with suspected heart failure. Statisticians in the Pharmaceutical Industry 2014 Conference

Factors associated with quality of life in patients with suspected heart failure. The European Society of Cardiology (ESC) Heart Failure 2013

Mortality risk stratification in chronic heart failure patients: an analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA). The ESC Congress 2012