Peter is an accomplished research scientist with over seven years of postdoctoral research experience. He is a Senior Lecturer in biomedical science and Director of our Biomedical Research Group.
Peter’s research experience is from a wide variety of settings; from the Clinical Pharmacology laboratory (1992-1995) ex. of Hans Krebs (Nobel Laureate) in the Radcliffe Infirmary, University of Oxford, to the Department of Pathology, University of Cambridge (1995-2000). His current and long-standing research interests are in the role of transglutaminase enzymes, during programmed cell death (apoptosis) and most recently in cancer and chemotheraputic drug resistance of hepatocarcinoma.
In recent years, this interest has extended to the study of erythropoetin and nitrogen oxide metabolism (NO) in explant tissue culture models of rheumatoid arthritis. Peter’s research experience informs his teaching.
Odii, B.O. and Coussons, P., 2014. Reduction of cisplatin cytotoxicity in Hepatocarcinoma cells by optimization of treatment conditions. International Journal of Scientific Research, November 2014, 3(11), pp.297-302.
Odii, B.O. and Coussons, P., 2014. History and Biology of Transglutaminase 2: A synopsis. International Journal of Biochemistry Research & Review, 4(1), pp.43-65.
McRobie, H., King, L., Fanutti, C., Martyn, F., Symmons, M. and Coussons, P., 2014. Agouti signalling protein is an inverse agonist to the wildtype and agonist to the melanic variant of the melanocortin-1 receptor in the grey squirrel (Sciurus carolinensis). FEBS Letts, 588(14), pp.2335-2343.
Odii B., O. and Coussons, P., 2014. Review, Biological Functionalities of Transglutaminase 2 and the Possibility of its Compensation by Other Members of the Transglutaminase Family. The Scientific World Journal, Hindawi Publishing Corporation.
McRobie, H., King L., Fanutti C., Coussons P., Moncrief N. and Thomas A., 2014. The melanocortin 1 receptor (MC1R) gene in the grey (Sciurus carolinensis), fox (Sciurus niger) and red (Sciurus vulgaris) squirrels: melanism is not associated with variation in the MC1R in the red and fox squirrel. J Hered, 105(3), pp.423-428.
Odii B. and Coussons P., 2012. Pharmacological Isolation of Experimental Models of Drug-resistant Hepatocellular Carcinoma Cell Line. Journal of Cancer Therapy, 3(4), pp.216-221.
Coussons, P., Fanutti, C., Baig, S., and Grant, R., 2011. Human recombinant erythropoietin (rHuEPO) modulates tissue remodelling in juvenile porcine cartilage explant tissue. International Journal of Experimental Pathology, 92, A49.
Odii, B. and Coussons, P., 2011. Pharmacological Isolation of Experimental Models of Drug-resistant Hepatocellular Carcinoma Cell Line. Journal of Cancer Therapy, 3, pp.216-221.
McRobie, H., King, L., Symmons, M., Fanutti, C. and Coussons, P., 2013. An eight amino acid deletion in the melanocortin-1-receptor leads to a constitutively active receptor in the grey squirrel (Sciurus carolinensis). Signalling 2013: From Structure to Function, University of York, 7-19 July 2013.
Laws, S., Gibbons, S., Khondkar, P., Mbaebie, B., Coussons, P. and Fanutti, C., 2012. In vitro screening of antimicrobial plant natural products against escherichia coli. Norwich Research Park Antibiotics Symposium: Obstacles, Opportunities and Innovations, University of East Anglia, Norwich, 17 July 2012.
Fanutti, C., Baig, S., Hussain, S., Davidson, R, Clark, I., Grant, R. and Coussons, P., 2012. Effects of fibroblast co-culture on the response of immature porcine cartilage explant tissue to erythropoietin and interleukin-1 beta in explant models of arthritic disease. European Congress in Immunology, Glasgow, 5-8 September 2012.
McRobie, H., Fanutti, C., Symmons, M.F. and Coussons, P. A model of the deletion mutant of melanocortin 1 receptor (MC1R-D24) derived from a melanic form of the grey squirrel (Sciurus carolinensis). Biochemical Society Conference: G-protein-coupled-receptors: from structural insights to functional mechanisms, Monash University Prato Centre, Italy, 12-14 September 2012.
Odii, B. and Coussons, P., 2012. Untangling the mechanism of cisplatin/5-fluorouracil therapy of liver cancer using a hepatocarcinoma cell line. Faculty of Science and Engineering, 2nd Annual Research and Scholarship Conference, Anglia Ruskin University, 23 May 2012.
Odii, B. and Coussons, P., 2012. Pharmacological isolation of experimental models of drug-resistant cells in hepatocellular carcinoma cell line. 6th Annual Research Student Conference, Anglia Ruskin University, 6 June 2012.
D'Arcy, M. and Coussons, P., 2012. Determination of the TG2 isoforms in the HepG2 (hepatocarcinoma) cell line. 6th Annual Research Student Conference, Anglia Ruskin University, 6 June 2012.
D'Arcy, M. and Coussons P., 2012. The role of transglutaminase 2 (TG2) in cancer. Faculty of Science and Engineering, 2nd Annual Research and Scholarship Conference, Anglia Ruskin University, 23 May 2012.
Coussons, P.J., Fanutti, C., Baig, S. and Grant, R., 2010. Human recombinant erythropoietin (rHuEPO) modulates tissue remodelling in juvenile porcine cartilage explant tissue. BSMB Autumn Meeting, Inflammation meets matrix biology, Norwich, 6-7 September 2010.