Dr Richard P O Jones

Richard contributes to teaching at levels 4-7 inclusive for the MSc in Applied Bioscience, the Institute of Biomedical Science (IBMS)-accredited MSc in Biomedical Science by distance learning and BSc (Hons) in Biomedical Science. He has many years of research experience in molecular biology, biochemistry, biophysics, and bioinformatics.

[email protected]

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Background

Before joining Anglia Ruskin in 2013, Richard completed four Postdoctoral Research Associate positions at Yale University (USA) and at the universities of Leeds, Manchester and York. In addition, he has held research positions at Zeneca Pharmaceuticals and at the British Petroleum Company Sunbury Research Centre.

Research interests

Richard’s research interests include biochemical, biophysical and bioinformatic studies of extracellular matrix and membrane proteins (retinoschisin, fibulin 5, fibronectin, collagen I, integrins, fibrinogen, bacterial surface proteins, oxacillin-hydrolysing proteins and toll-like receptors) implicated in antibiotic resistance and human eye, skin and vascular diseases. He collaborates with Professor Clair Baldock and Dr Tao Wang (University of Manchester, UK), Dr Ben Evans (University of East Anglia) and Drs James Sullivan, Grisha Pirianov and Felicity Savage (ARU).

Areas of research supervision

As leader of the Masters Project Module, Richard co-supervises students’ projects that are performed in the NHS often using samples obtained from patients or with the aim of improving laboratory services. His broad background has enabled him to supervise undergraduate students’ final year bioinformatics analyses of a variety of proteins, and literature / meta-analyses projects and case studies in areas that include the following: dystonia; Huntington’s disease; myasthenia gravis; generalized anxiety disorder; legal and illegal highs; cardiac infection; foods for treatment of diseases; heart disease and biomarkers; cancer biomarkers; diabetes; retinopathies; lineolic acids; and osteoporosis.

Teaching

MSc Biomedical Science
Course Leader
Module Leader for Moving towards Mastery
Module Leader for General Pathology
Module Leader for Research Methods in Biomedical Science
Module Leader for Control Mechanisms in Health and Disease
Module Leader for Decision Making in Clinical Chemistry
Module Leader for Masters Project
Contributes to Cellular Haematology
Contributes to Blood Transfusion and Haemostasis

Qualifications

Postgraduate Certificate in Learning and Teaching in Higher Education - Anglia Ruskin University (2014).

MB ChB in Medicine and Surgery - University of Leeds School of Medicine (2001).

PhD in High Resolution and In Vivo NMR Spectroscopy - University of Manchester Department of Chemistry and Zeneca Pharmaceuticals Department of Cardiovascular and Musculoskeletal Research (1994)

BSc (First Class Honours) in Chemistry and Molecular Physics - University of Nottingham (1990)

Memberships, editorial boards

Fellow of the Higher Education Academy & of ARU

Fellow of Anglia Ruskin University

Member of the Biochemical Society and Local Ambassador for ARU

Member of the ARU Biomedical Research Group

Manuscript Reviewer for the Journal of Cellular and Molecular Medicine (Wiley).

Editorial Board Member, Materials Science in Semiconductor Processing (MSSP, Elsevier)

Research grants, consultancy, knowledge exchange

Richard has won six grants over the last three years to support the Current Advances in Biomedical Science module’s annual Scientific Conference Day.

Selected recent publications

Ramsey, E. P., Collins, R. F., Owens, T. W., Siebert, C. A., Jones, R. P. O., Wang, T., Roseman, A. M., Baldock, C., 2016. Structural analysis of x-linked retinoschisis mutations reveals distinct classes which differentially effect retinoschisin function. Human Molecular Genetics, 25(24), pp. 5311-5320. doi: 10.1093/hmg/ddw345

Jones, R. P. O., Milner, N., 2014. Meeting Report – Biomedical Research Conference, 9 April 2014, Anglia Ruskin University, Cambridge, UK. The Biochemist, 36(5), p. 68.

Stemberk, V., Jones, R. P. O., Moroz, O., Atkin, K. E., Edwards, A. M., Turkenburg, J. P., Leech, A. P., Massey, R. C. and Potts, J. R., 2014. Evidence for steric regulation of fibrinogen binding to Staphylococcus aureus fibronectin-binding protein A (FnBPA). Journal of Biological Chemistry, 289, pp. 12842-12851. doi: 10.1074/jbc.M113.543546

Miles, J. R., Willis, M. R., Jones, R. P. O., 2012. Photoconduction properties of some monomeric phthalocyanines and dibromoanthrone. Materials Science in Semiconductor Processing, 15(1), pp. 61-72. doi: 10.1016/j.mssp.2011.08.006

Norris, N. C., Bingham, R. J., Harris, G., Speakman, A., Jones, R. P. O., Leech, A., Turkenburg, J. P., Potts, J. R., 2011. Structural and functional analysis of the tandem beta-zipper interaction of a streptococcal protein with fibronectin. Journal of Biological Chemistry, 286(44), pp. 38311-38320. doi: 10.1074/jbc.M111.276592

Kirilenko, P., He, G., Mankoo, B., Mallo, M., Jones, R. P. O., Bobola, N., 2011. Transient activation of Meox1 is an early component of the gene regulatory network downstream of Hoxa2. Molecular and Cellular Biology, 31(6), pp. 1301-1308. doi: 10.1128/MCB.00705-10.

Kuruvatti, J., Prasad, V., Williams, R., Harrison, M. A., Jones, R. P. O., 2011. Motivations for Donating Blood and Reasons Why People Lapse or Never Donate in Leeds, England: A 2001 Questionnaire-Based Survey. Vox Sanguinis, 101(4), pp. 333-338. doi: 10.1111/j.1423-0410.2011.01488.x

Gui, J., Wang, T., Jones, R. P. O., Trump, D., Zimmer, T., Lei, M., 2010. Multiple loss-of-function mechanisms contribute to SCN5A-related familial sick sinus syndrome. PLoS One, 5(6), e10985. doi: 10.1371/journal.pone.0010985

Jones, R. P. O., Durose, L. J., Phillips, C., Keen, J. N., Findlay, J. B. C., Harrison, M. A., 2010. A site-directed cross-linking approach to the characterization of subunit E-G contacts in the V-ATPase stator. Molecular Membrane Biology, 27(4-6), pp. 147-59. doi: 10.3109/09687681003796441

Jones, R. P. O., Ridley, C., Jowitt, T. A., Wang, M-C., Howard, M., Bobola, N., Wang, T., Bishop, P. N., Kielty, C. M., Baldock, C., Lotery, A. J., Trump, D., 2010. Structural effects of fibulin 5 mutations associated with age-related macular degeneration & cutis laxa. Investigative Ophthalmology & Visual Science, 51(5), pp. 2356-62. doi: 10.1167/iovs.09-4620

Recent presentations and conferences

Attends the ARU Faculty of Science and Technology Annual Research and Scholarship Conference.

Recent oral research presentation: Jones, R.P.O., 4th November 2015. Extracellular matrix proteins implicated in human eye, skin and vascular diseases. ARU Faculty of Science and Technology Department of Biomedical and Forensic Sciences Research Seminar Series.

Media experience

Writing media articles that report on scientific meetings and research.