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Join ARU's Medical Technology Research Centre (MTRC) for an online seminar from Dr Alice Lapthorn on our work to identify novel drugs using a high-throughput screening assay.
Although hypertrophic scarring affects ~91% of burn patients annually, there is no drug to prevent this common complication. Hypertrophic scars are a fibroproliferative disorder, caused by dysregulated wound healing. This can be characterised by persistent myofibroblast transformation and the excessive accumulation of extracellular matrix (ECM).
Our research has focussed on developing a high-throughput screening assay that utilises the myofibroblast phenotype, to identify novel drugs that could be repurposed as a therapeutic for the prevention of hypertrophic scarring.
Contact MTRC@aru.ac.uk for more information.