Fibrosis is the cause of 45% of mortality in the Western world, yet we have no safe and effective treatments.
A key aspect of fibrosis is the conversion of quiescent fibroblasts to so-called myofibroblasts. These cells are responsible for excessive extracellular matrix formation which can cause scarring and ultimately organ failure.
This research seminar will shine a light on different aspects of myofibroblast biology (such as extracellular vesicles and temporal gene expression profiles) and how our lab attempts to target it to find novel treatment options for fibrosis.
Contact MTRC@aru.ac.uk for more information.