Improving care for older cancer patients through Comprehensive Geriatric Assessment

Cancer patients over the age of 65 years are at increased risk of health deterioration during cancer treatment. Key to supporting this potentially vulnerable population throughout cancer treatment is identifying needs and health status, so that individualised and supportive cancer care can be developed. To facilitate this, Comprehensive Geriatric Assessment (CGA) can be carried out on patients over 65 years to determine if the are “fit”, “vulnerable” or “frail”. This assessment can be used as a treatment guide to improve outcomes and quality of life for older patients.

In a series of projects, colleagues at General Hospital Groeninge, Belgium, led by honorary visiting Professor Philip Debruyne, have been using the Comprehensive Geriatric Assessment (CGA) as a screening tool to explore the needs of the older cancer patient population, building the evidence base regarding best practice and supportive cancer care for this group.

For further information related to this work, please contact Professor Philip Debruyne

Funding & collaborators

This work was funded through Kortrijk Oncology Fund, King Baudouin FoundationBrussels, Belgium,and Belgian Stand Up Against Cancer action (Kom Op Tegen Kanker)

Professor Philip Debruyne, AZ Groeninge Hospital, Honorary Visiting Professor ARU
Laura Tack AZ Groeninge Hospital

Dr. Laurence Goethals AZ Groeninge Hospital
Lore Ketelaars  AZ Groeninge Hospital
Jolien De Zutter AZ Groeninge Hospital
Professor Tom Boterberg Ghent University 

Professor Sylvie Rottey Ghent University 

Professor Fréderic Duprez Ghent University 
Professor Hans Wildiers UZ Leuven 
Cindy Kenis UZ Leuven

Dr Brendon Stubbs ARU 

Professor Patricia Schofield

 

 

Publications 

Pottel L, Boterberg T, Pottel H, Goethals L, Van Den Noortgate N, Duprez F, De Neve W, Rottey S, Geldhof K, Van Eygen K, Kargar-Samani K, Ghekiere V, Cornelis F, Mohile S & Debruyne PR. (2012). Determination of an adequate screening tool for identification of vulnerable elderly head and neck cancer patients treated with radio(chemo)therapy. J Geriatr. Oncol. 3(1),24-32. doi: https://doi.org/10.1016/j.jgo.2011.11.006

Pottel L, Lycke M, Boterberg T, Pottel H, Goethals L, Duprez F, Van Den Noortgate N, De Neve W, Rottey S, Geldhof K, Buyse V, Kargar-Samani K, Ghekiere V & Debruyne PR (2014). Serial comprehensive geriatric assessment in elderly head and neck cancer patients undergoing curative radiotherapy identifies evolution of multidimensional health problems and is indicative of quality of life. Eur J Cancer Care (Engl). 23(3):401-12. doi: 10.1111/ecc.12179. Epub 2014 Jan 28.

Pottel L, Lycke M, Boterberg T, Pottel H, Goethals L, Duprez F, Rottey S, Lievens Y, Van Den Noortgate N, Geldhof K, Buyse V, Kargar-Samani K, Ghekiere V & Debruyne PR. (2015). G-8 indicates overall and quality-adjusted survival in older head and neck cancer patients treated with curative radiochemotherapy. BMC Cancer. 15:875. doi: 10.1186/s12885-015-1800-1.

Tack L, Lefebvre T, Lycke M, Pottel L, Cool L, Ketelaars L, De Zutter J, Martens E, Pottel H, Stellamans K, Van Eygen K, Werbrouck P, Vergauwe P, Wildiers H, Schofield P, Boterberg T, & Debruyne PR. (2020). Underrepresentation of vulnerable older patients with cancer in phase II and III oncology registration trials: A case-control study. J Geriatr Oncol. 11(2):320-326. doi: 10.1016/j.jgo.2019.09.003. Epub 2019 Oct 14.
Lycke M, Martens E, Ketelaars L, Dezutter J, Lefebvre T, Pottel H, Van Eygen K, Cool L, Schofield P, Boterberg T & Debruyne PR. (2019). Detection of alcohol abuse in older patients with cancer: The integration of alcohol screening questionnaires in the comprehensive geriatric assessment. J Geriatr Oncol. 10(5):819-823. doi: 10.1016/j.jgo.2019.02.009. Epub 2019 Feb 26. 
Lycke M, Ketelaars L, Martens E, Lefebvre T, Pottel H, Van Eygen K, Cool L, Pottel L, Kenis C, Schofield P, Boterberg T & Debruyne PR. (2019). The added value of an assessment of the patient's hand grip strength to the comprehensive geriatric assessment in G8-abnormal older patients with cancer in routine practice. J Geriatr Oncol. 10(6):931-936. doi: 10.1016/j.jgo.2019.01.001. Epub 2019 Jan 11.